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By Gethin Morgan, Stuart Butler

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Extra info for Seminars in Basic Neurosciences (College Seminars Series)

Sample text

Repolarisation of the membrane is associated with the closing of the voltage-gated sodium channels and opening of voltage-gated potassium channels. e. no further action potentials can be elicited, even with greatly increased stimuli). This is due t0 v0ltage—dependent inactivation ei Nat channels, which cannot reach their ‘closed’ state until the membrane is repolarised, at which point they can be ‘opened’ in response to a stimulus (see Fig. 1). During the last part ofthe action potential there is a relative refractory period, when increasing stimulus strength will produce an action potential.

Ln other vertebrates they possibly assist the detection of olfactory gradients when tracking scents. Motor systems Upper and lower motor neurons Skeletal muscle is innervated by neurons which have their cell bodies in the ventral horns of the spinal cord and in the motor nuclei of the cranial nerves. All movement is controlled by these neurons, which act as the final common pathway to the muscle. This final common pathway is referred to as the lower motor neuron (LMN). The neural systems of the brain and spinal cord which converge upon it are known collectively as the upper motor neuron (UMN).

New York: Freeman. Kimura, D. (1983) Speech representation in an unbiased sample of left handers. Human Neurobiology, 2, 147-154. Snell, R. S. (1987) Clinical Neuroanatomy for Medical Students (2nd edn). Boston: Little, Brown. Walsh, l<. W. (1987) Neuropsychology: A Clinical Approach (2nd edn). Edinburgh: Churchill Livingstone. Recommended texts Barr, M. L. (1988) The Human Nervous System (5th edn). New York: Lippincott. Heimer, L. (1983) The Human Brain and Spinal Cord. New York: Springer-Verlag.

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