Neuromodulation in Psychiatry by Clement Hamani, Paul Holtzheimer, Andres M. Lozano, Helen PDF

By Clement Hamani, Paul Holtzheimer, Andres M. Lozano, Helen Mayberg

Edited by means of a professional multidisciplinary team, Neuromodulation in Psychiatry is the 1st reference advisor to deal with either invasive and non-invasive neuromodulation techniques utilized in psychiatry.

  • Covers simple rules, technical points, scientific functions and moral considerations
  • Presents updated facts in complete summaries compatible for all degrees of experience
  • Each strategy is obviously defined in addition to its implications for real-world scientific practice
  • Allows psychiatrists to make proficient judgements relating to neuromodulation for his or her patients

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Extra info for Neuromodulation in Psychiatry

Sample text

Informed consent In order to respect the autonomy of a patient or research subject, a clinician or researcher must acquire their informed consent [3]. Such a requirement is consistent with the Belmont Report’s respect for persons principle, although this connection is perhaps over asserted [29, 30]. A successful informed consent process will contain an explicit discussion of the risks and benefits of an intervention, along with an acknowledgement of any uncertainties and a clear statement of the expected result [27].

OCD patients have enhanced metabolic rates in the striatum [17]; this increases even further during symptom prov­ ocation [83, 84]. This effect reduces with successful therapeutic intervention [85]. ­ Interestingly, the striatal effects for OCD are largely observed in the rostral striatum where prefrontal inputs converge (see previous text). Resting state studies have revealed that OCD patients have increased functional con­ nectivity between the ventral PFC (vPFC) and the striatum [86–88], providing further evi­ dence that prefrontal cortico‐striatal networks are central to this disorder.

2005;45:651–60. 21 Schiff N, Giacino J, Kalmar K, Victor J, Baker K, Gerber M, et al. Behavioral Improvements with Thalamic Stimulation After Severe Traumatic Brain Injury. Nature. 2007;448:600–3. 22 Synofzik M, Schlaepfer TE. Stimulating Personality: Ethical Criteria for Deep Brain Stimulation in Psychiatric Patients and for Enhancement Purposes. Biotechnol J. 2008;3: 1511–20. 23 Fins JJ. Neuroethics and the Lure of Technology. In: Illes J, Sahakian BJ, editors. Oxford Handbook of Neuroethics.

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